LipidFun: a database of lipid functions

The Phenotype section offers detailed information on the user-selected phenotype and its associated lipid. The results included:
  • A summary table of phenotype-lipids association.
  • An evidence table of phenotype-lipids association.
  • A phenotype-lipids association network.
  • A phenotype-lipids association inferred tree view.
  • A phenotype-lipids association wordcloud.
Enter the phenotype name in the selection box to analyze your desired phenotype. If you are unsure how to use our website, check out the example below the selection box or refer to the tutorial for guidance.


We support phenotype search by common name, alias, and MeSH ID.

Example : Fatty Liver, Obesity, D003920




This table displays lipids associated with the target phenotype, providing their names and the number of related phenotypes. Additional details include specificity index, pleiotropy index, the count of literature references mentioning a specific phenotype-lipid association and the earliest and latest literature mentioning this association.

  • Click on a count in the "Literature" column to view sentences in literature containing the target phenotype and a specific lipid .




The evidence table provides the sentences extracted from literature references mentioning the target phenotype and a specific lipid. The table includes additional information such as each reference's PMID (PubMed ID), the count of literature references mentioning the phenotype-lipid association, whether the associations are under expert curation, and the publication year.

  • Click on a specific PMID to directly access its full article in PubMed.
  • In each sentence, phenotype, lipid, and verbs are highlighted for clarity as Phenotype, Lipid, and Verb.
    Please note that if a word is supposed to be highlighted by more than two colors, it will be displayed in grey.





The network visualizes lipids associated with the target phenotype. Node sizes and colors represent the literature records documenting the phenotype-lipid association. Nodes without literature are marked white, while nodes with more literature records are red. You can manipulate the network by clicking on the toolbar at the bottom right and left.

  • Zoom in or out of the network by scrolling the mouse wheel and can move it by clicking and dragging it.
  • Hover over a specific node to view the count of literature that mention this lipid and target phenotype.
  • Double click on a colored node to access the evidence table listing all the relevant sentences extracted from the literature.




The inferred tree visualizes lipids associated with the target phenotype based on Lipidmaps and lipid classification structure in MeSH (Medical Subject Headings). Node sizes indicate the total counts of downstream nodes' literature references. Each node's color is based on the literature count of the node itself. Nodes without literature are marked in white, while nodes with more literature records are near red. Nodes with a bold frame indicate the presence of downstream nodes, and you can click on them to expand their downstream nodes.

  • Click on the bold frame nodes to expand or collapse their associated downstream nodes.
  • Hover over a specific node to view the node literature count and downstream literature count.
  • Click on a colored node to access the evidence table listing all the relevant sentences extracted from the literature.




The word cloud presents lipids associated with the target phenotype. Lipid names displayed in larger sizes represent more literature documenting this phenotype-lipid association.

  • Hover over a specific lipid name to view the count of literature that mention this lipid and target phenotype.
  • Click on a specific lipid name to access the evidence table listing all the relevant sentences extracted from the literature.




The left bar plot displays the top 10 associated biological functions based on the correlation coefficient. The x-axis shows biological function names, and the y-axis shows correlation coefficient values.

On the right, the Sankey diagram illustrates how the targeted phenotype is associated with lipids and biological functions. The connecting lines between nodes represent the associations, with thicker lines indicating stronger associations.